Kudyasheva A., Zagorskaya N. The relationship between individual indicators of phospholipids composition in the liver of tundra voles living in the conditions of increased radioacivity // Principy èkologii. 2018. № 2. P. 75‒86. DOI: 10.15393/j1.art.2018.6742

Issue № 2

Original research


The relationship between individual indicators of phospholipids composition in the liver of tundra voles living in the conditions of increased radioacivity

   Alevtina Grigor
D.Sc., Institute of Biology, Komi Scientific Center, Ural Division RAS, kud@ib.komisc.ru
   Nadezhda Gavrilovna
Institute of Biology, Komi Scientific Center, Ural Division RAS, zagorskya@ib.komisc.ru
Increased level of radioactivity
population phase
Microtus Oeconomus
relationship between phospholipid fractions
Summary: Lipid peroxidation plays an important role in the adaptation of animals to environmental pollution with radionuclides. We studied some mechanisms of cellular metabolism regulation in in tunra voles living in the conditions of environmental radioactive pollution (the Komi Republic, Ukhta region) in different periods of population size (peak and decline phase). By the comparative biochemical analysis, we established that the character and tendency of interlinks between the major and minor fractions of phospholipids and total composition of liver phospholipids depended on physicochemical parameters of lipids. These differences depended on a population cycle phase and the radioactivity level of a particular plot, the severity of which was due to initial lipid peroxidation parameters and the degree of lipid unsaturation in a study tissue. The correlation coefficient between the compared fractions of phospholipids increased with the enhancement of pollution observed in both phases (pick and decline). Technogenic radioactive pollution of the radium plot provides the modification of lipid bi-layer properties of liver cell membranes, changes their physicochemical properties, in some cases destructed interrelation between normally coordinated parameters, and provides adaptation at the cell level. Intrapopulation factors have a modifying effect on the intensity of some links of the liver lipid peroxygenation in tundra voles. The noted features of the regulation system of lipid peroxidation in the liver of tundra voles are not specific and typical only for the impact of radiation. They can also occur under the influence of low intensity factors of physical and chemical nature.

© Petrozavodsk State University

Received on: 21 July 2017
Published on: 30 June 2018


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